Black Box Explains... Smart Serial Interface.
Smart Serial is the Cisco router interface. It uses a space-saving 26-pin connector that automatically detects RS-232, RS-449, RS-530, X.21, and V.35 interfaces for both DTE and DCE devices based on the type of cable used.
Smart Serial connectors can be found on Smart Serial cables and on the dual-serial-port WAN interface cards used in Cisco 2600 and 1720 series routers. The cables feature a Smart Serial connector on one end and a standard cable connector (such as DB25 or V.35) on the other end. The Smart Serial connector attaches to the dual-serial-port WAN interface card.
Each port on the WAN interface card features a Smart Serial connector. Ports can be configured independently to support two different physical interfaces. For example, you can run RS-232 cable to one port and RS-449 cable to the other port using a single WAN interface card.
What if you need to replace that RS-232 cable with V.35 cable? Just plug a Smart SerialV.35 cable into the port. Because any Smart Serial connector on the WAN interface card attaches to any Smart Serial cable connector, no additional interface or adapter is necessary. Changing the configuration of your network is literally a snap!